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Publication in Osteoarthritis & Cartilage

“Model-based evaluation of cost-effectiveness of nerve growth factor inhibitors in knee osteoarthritis: Impact of drug cost, toxicity, and means of administration” is an original research article examining the cost and toxicity thresholds under which a nerve growth factor inhibitor (NGF-i) would be a cost-effective treatment for knee OA patients. Given the high cost of drug administration in a hospital setting, we found that these agents are not cost-effective if they require intravenous hospital administration. However, if administration of the drug occurs at home and they are proven to have minimal effect on NGF-is could be a cost-effective treatment option

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