skip to Main Content
MGB-BWH logo

The Osteoarthritis Policy Model has produced the manuscripts below. Check back regularly for new publications.

Bensen GP, Rogers AC, Leifer VP, Edwards RR, Neogi T, Kostic AM, Paltiel AD, Collins JE, Hunter DJ, Katz JN, Losina E. Does gabapentin provide benefit for patients with knee OA? A benefit-harm and cost-effectiveness analysis. Osteoarthritis and cartilage. 2022 November 19. PMID: 36414225.
 

Kostic AM, Leifer VP, Selzer F, Hunter DJ, Paltiel AD, Chen AF, Robinson MK, Neogi T, Collins JE, Messier SP, Edwards RR, Katz JN, Losina E. The Cost-Effectiveness of Weight Loss Interventions Prior to Total Knee Replacement for Patients with Class III Obesity. Arthritis Care and Research. 2022 October 17. PMID: 36250415.
 

Williams EE, Katz JN, Leifer VP, Collins JE, Neogi T, Suter LG, Levy B, Farid A, Safran-Norton CE, Paltiel AD, Losina E. Cost-Effectiveness of Arthroscopic Partial Meniscectomy and Physical Therapy for Degenerative Meniscal Tear. ACR Open Rheumatology. 2022 July 21. PMID: 35866194.
 

Kostic AM, Leifer VP, Gong Y, Robinson MK, Collins JE, Neogi T, Messier SP, Hunter DJ, Selzer F, Suter LG, Katz JN, Losina EL. The Cost-Effectiveness of Surgical Weight Loss Interventions for Patients with Knee Osteoarthritis and Class III Obesity. Arthritis Care and Research. 2022 June 3. PMID: 35657632.
 

Huizinga JL, Stanley EE, Sullivan JK, Song S, Hunter DJ, Paltiel AD, Neogi T, Edwards RR, Katz JN, Losina E. Societal Cost of Opioid Use in Symptomatic Knee Osteoarthritis Patients in the United States. Arthritis Care Research. 2022 May 10. PMID: 33629485.
 

Losina E, Song S, Benson GP, Katz JN. Opioid use among Medicare beneficiaries with knee osteoarthritis: prevalence and correlates of chronic use. Arthritis Care & Research. 2021 December 17. PMID: 34919346.
 

Chen AT, Bronsther CI, Stanley EE, Paltiel AD, Sullivan JK, Collins JE, Neogi T, Katz JN, Losina E. The Value of Total Knee Replacement in Patients With Knee Osteoarthritis and a Body Mass Index of 40 kg/m2 or Greater : A Cost-Effectiveness Analysis. Ann Intern Med. 2021 March 23. PMID: 33750190.
 

Stanley EE, Trentadue TP, Smith KC, Sullivan JK, Thornhill TS, Lange J, Katz JN, Losina E. Cost-effectiveness of dental antibiotic prophylaxis in total knee arthroplasty recipients with type II diabetes mellitus. Osteoarthritis and Cartilage Open. 2020 December 22. Read it here.
 

Lenhard NK, Sullivan JK, Ross EL, Song S, Edwards RR, Hunter DJ, Neogi T, Katz JN, Losina E. Does screening for depressive symptoms help optimize duloxetine use in knee OA patients with moderate pain? A cost-effectiveness analysis. Arthritis Care Res (Hoboken). 2020 November 30. PMID: 33253496.
 

Sullivan JK, Huizinga J, Edwards RR, Hunter DJ, Neogi T, Yelin E, Katz JN, Losina E. Cost-effectiveness of duloxetine for knee OA subjects: The role of pain severity. Osteoarthritis Cartilage. 2020 November 6. PMID: 33171315.
 

Losina E, Silva GS, Smith KC, Collins JE, Hunter DJ, Shrestha S, Messier SP, Yelin EH, Suter LG, Paltiel AD, Katz JN. Quality-Adjusted Life-Years Lost Due to Physical Inactivity in a US Population With Osteoarthritis. Arthritis Care Res (Hoboken). 2020 October 1. PMID: 31350803.
 

Silva GS, Sullivan JK, Katz JN, Messier SP, Hunter DJ, Losina E. Long-term clinical and economic outcomes of a short-term physical activity program in knee osteoarthritis patients. Osteoarthritis and Cartilage. 2020 March 10. PMID: 32169730.

Smith KC, Losina E, Messier SP, Hunter DJ, Chen AT, Katz JN, Paltiel AD. Budget Impact of Funding an Intensive Diet and Exercise Program for Overweight and Obese Patients With Knee Osteoarthritis. ACR Open Rheumatology. 2020 January. PMID: 31943972.

Losina E, Silva GS, Smith KC, Collins JE, Hunter DJ, Shrestha S, Messier SP, Yelin EH, Suter LG, Paltiel AD, Katz JN. Quality-adjusted life-years lost due to physical inactivity in the United States osteoarthritis population. Arthritis Care and Research. 2019 July 26. PMID: 31350803.

Smith KC, Paltiel AD, Yang HY, Collins JE, Katz JN, Losina E. Cost-effectiveness of health coaching and financial incentives to promote physical activity after total knee replacement. Osteoarthritis Cartilage. 2018 Aug 6. PMID: 30092263.

Losina E, Smith KC, Paltiel AD, Collins JE, Suter LG, Hunter DJ, Katz JN, Messier SP. Cost-effectiveness of diet and exercise for overweight and obese knee osteoarthritis patients. Arthritis Care Res (Hoboken). 2018 Jul 28. PMID: 30055077.

Losina E, Usiskin IM, Smith SR, Sullivan JK, Smith KC, Hunter DJ, Messier SP, Paltiel AD, Katz JN. Cost-effectiveness of generic celecoxib in knee osteoarthritis for average-risk patients: A model-based evaluation. Osteoarthritis Cartilage. 2018 Feb 23. PMID: 29481917.

Kerman HM, Smith SR, Smith KC, Collins JE, Suter LG, Katz JN, Losina E. Disparities in total knee replacement: Population losses in quality-adjusted life years due to differential offer, acceptance, and complication rates for Black Americans. Arthritis Care Res (Hoboken). 2018 Jan 24. PMID: 29363280.

Abbott JH, Usiskin IM, Wilson R, Hansen P, Losina E. The quality-of-life burden of knee osteoarthritis in New Zealand adults: A model-based evaluation. PLoS One. 2017 Oct 24;12(10). PMID: 29065119

Suter LG, Smith SR, Katz JN, Englund M, Hunter DJ, Frobell R, Losina E. Projecting Lifetime Risk of Symptomatic Knee Osteoarthritis and Total Knee Replacement in Individuals Sustaining a Complete Anterior Cruciate Ligament Tear in Early Adulthood. Arthritis Care Res (Hoboken). 2017 Feb;69(2):201-208. PMID: 27214559

Smith SR, Katz JN, Collins JE, Solomon DH, Jordan JM, Suter LG, Yelin EH, Paltiel AD, Losina E. Cost-effectiveness of tramadol and oxycodone in the treatment of knee osteoarthritis. Arthritis Care Res (Hoboken). 2017 Feb;69(2):234-242. PMID: 27111538

Deshpande BR, Katz JN, Solomon DH, Yelin EH, Hunter D, Messier SP, Suter LG, Losina E. The number of persons with symptomatic knee osteoarthritis in the United States: Impact of race/ethnicity, age, sex, and obesity. Arthritis Care Res (Hoboken). 2016 Dec;68(12):1743-1750. PMID: 27014966

Losina E, Michl G, Collins JE, Hunter DJ, Jordan JM, Yelin E, Paltiel AD, Katz JN.  Model-based evaluation of cost-effectiveness of Nerve Growth Factor Inhibitors in Knee Osteoarthritis: Impact of drug cost, toxicity, and means of administration.  Osteoarthritis Cartilage. 2016 May;24(5):776-85. PMCID: PMC4838505

Katz JN, Smith SR, Collins JE, Solomon DH, Jordan JM, Hunter DJ, Suter LG, Yelin E, Paltiel AD, Losina E. Cost-effectiveness of nonsteroidal anti-inflammatory drugs and opioids in the treatment of knee osteoarthritis in older patients with multiple comorbidities. Osteoarthritis Cartilage. 2016 Mar;24(3):409-18. PMCID: PMC4761310

Losina E, Dervan EE, Paltiel AD, Dong Y, Wright RJ, Spindler KP, Mandl LA, Jones MH, Marx RG, Safran-Norton CE, Katz JN. Defining the value of future research to identify the preferred treatment of meniscal tear in the presence of knee osteoarthritis. PLoS One. 2015; 10(6). PMID 26086246

Losina E, Paltiel AD, Weinstein AM, Yelin E, Hunder DJ, Chen SP, Klara K, Suter LG, Solomon DH, Burbine SA, Walensky RP, Katz JN. Lifetime medical costs of knee osteoarthritis management in the United States: Impact of extending indications for total knee arthroplasty. Arthritis Care Res (Hoboken). 2015; 67(2): 203-15. PMID 25048053

Wright EA, Katz JN, Abrams S, Solomon DH, Losina E. Trends in prescription of opioids from 2003-2009 in persons with knee osteoarthritis. Arthritis Care & Research. 2014 October; 66(10): 1489-95. PMID 24782079

Collins JE, Katz JN, Dervan EE, Losina E. Trajectories and Risk Profiles of Pain in Persons with Radiographic, Symptomatic Knee Osteoarthritis: Data from the Osteoarthritis Initiative. Osteoarthritis and Cartilage. 2014 May; 22(5):622-30. PMID 24662734

Losina E,  Burbine SA, Suter LG, Hunter DJ, Solomon DH, Daigle ME, Dervan EE, Jordan JM, Katz JN. Pharmacologic regimens for knee osteoarthritis prevention: can they be cost-effective? Osteoarthritis and Cartilage. 2014 Mar; 22(3): 415-430. PMID 24487044

Losina E, Dervan EE, Daigle ME, Katz JN. Studies of pain management in osteoarthritis: bedside to policy. Osteoarthritis and Cartilage. 2013 Sept; 21(9): 1264-71. PMID 23973140

Suter LG, Paltiel AD, Rome BN, Solomon DH, Thornhill TS, Abrams SK, Katz JN, Losina E. Placing a price on medical device innovation: The example of total knee arthroplasty. PLoS ONE. 2013; 8(5).

Losina E, Daigle ME, Suter LG, Hunter DJ, Solomon DH, Walensky RP, Jordan JM, Burbine SA, Paltiel AD, Katz JN. Disease-modifying drugs for knee osteoarthritis: Can they be cost-effective? Osteoarthritis and Cartilage. 2013 May; 21(5): 655-67. PMID 23380251

Weinstein AM, Rome BN, Reichmann WM, Collins JE, Burbine SA, Thornhill TS, Wright J, Katz JN, Losina E. Estimating the burden of total knee replacement in the United States. J Bone Joint Surg Am. 2013 Mar 6;95(5):385-92. PMID 23344005

Collins JE, Katz JN, Donnell-Fink LA, Martin SD, Losina E. Cumulative incidence of ACL reconstruction after ACL injury in adults: role of age sex and race. Am J Sports Med. 2013 Mar;41(3):544-9.  PMID 23302260

Losina E, Weinstein AM, Reichmann WM, Burbine SA, Solomon DH, Daigle ME, Rome BN, Chen SP, Hunter DJ, Suter LG, Jordan JM, Katz JN. Lifetime risk and age of diagnosis of symptomatic knee osteoarthritis in the US. Arthritis Care and Res (Hoboken). 2013 May; 65(5): 703-11. PMID 23203864

Daigle ME, Weinstein AM, Katz JN, Losina E. The cost-effectiveness of total joint arthroplasty: A systematic review of published literature. Best Practice & Research Clinical Rheumatology. 2012 Oct; 26(5):649-58. PMID 23218429

Losina E, Thornhill TS, Rome BN, Wright J, Katz JN. The dramatic increase in total knee replacement utilization rates in the United States cannot be fully explained by growth in population size and the obesity epidemic. Journal of Bone and Joint Surgery. American Volume. 2012 Feb 1;94(3):201-7. PMID 22298051

Suter LG, Paltiel AD, Rome BN, Solomon DH, Golovaty I, Gerlovin H, Katz JN, Losina E. Medical device innovation–is “better” good enough? New England Journal of Medicine. 2011;365(16):1464-1466. PMID22010911

Reichmann WM, Katz JN, Losina E. Differences in self-reported health in the Osteoarthritis Initiative (OAI) and Third National Health and Nutrition Examination Survey (NHANES-III). PLoS One. 2011;6(2):e17345. PMID21387001

Losina E, Walensky RP, Reichmann WM, Holt HL, Gerlovin H, Solomon DH, Jordan JM, Hunter DJ, Suter LG, Weinstein AM, Paltiel AD, Katz JN. Impact of obesity and knee osteoarthritis on morbidity and mortality in older Americans. Annals of Internal Medicine. 2011;154(4):217-226. PMID21320937

Holt HL, Katz JN, Reichmann WM, Gerlovin H, Wright EA, Hunter DJ, Jordan JM, Kessler CL, Losina E. Forecasting the burden of advanced knee osteoarthritis over a 10-year period in a cohort of 60-64 year-old US adults. Osteoarthritis and Cartilage. 2011;19(1):44-50. PMID20955807

Wright EA, Katz JN, Cisternas MG, Kessler CL, Wagenseller A, Losina E. Impact of knee osteoarthritis on health care resource utilization in a US population-based national sample. Medical Care. 2010;48(9):785-791. PMID20706165

Suter LG, Fraenkel L, Losina E, Katz JN, Gomoll AH, Paltiel AD. Medical decision making in patients with knee pain, meniscal tear, and osteoarthritis. Arthritis and Rheumatism. 2009;61(11):1531-1538. PMID19877094

Reichmann WM, Katz JN, Kessler CL, Jordan JM, Losina E. Determinants of self-reported health status in a population-based sample of persons with radiographic knee osteoarthritis. Arthritis and Rheumatism. 2009;61(8):1046-1053. PMID19644892

Losina E, Walensky RP, Kessler CL, Emrani PS, Reichmann WM, Wright EA, Holt HL, Solomon DH, Yelin E, Paltiel AD, Katz JN. Cost-effectiveness of total knee arthroplasty in the United States: patient risk and hospital volume. Archives of Internal Medicine. 2009;169(12):1113-1121; discussion 1121-1112. PMID19546411

Cisternas MG, Yelin E, Katz JN, Solomon DH, Wright EA, Losina E. Ambulatory visit utilization in a national, population-based sample of adults with osteoarthritis. Arthritis and Rheumatism. 2009;61(12):1694-1703. PMID19950315

Emrani PS, Katz JN, Kessler CL, Reichmann WM, Wright EA, McAlindon TE, Losina E. Joint space narrowing and Kellgren-Lawrence progression in knee osteoarthritis: an analytic literature synthesis. Osteoarthritis and Cartilage. 2008;16(8):873-882. PMID18280757

Back To Top